The Spring 2017 Lab

The Spring 2017 Lab
Rina, Mauro, Debs, Rob, Daniel

Lab Members

Debs Gore-Lloyd
Rob Hicks
Mauro Moreno
Why is Batrachochytrium dendrobatidis such a baddie? Recent work by John Abramyan and Jason Stajich from the Stajich lab at UCR shows that there is genomic evidence for a chitin binding motif (CBM18) expansion that has occurred in the fungus, and this motif may very well be linked to an expansion of virulence factors. Previous work on B. dendrobatidis from Suzanne Joneson et al has shown expansion in several gene families including some with CBM18 domains. This work fits into the larger picture of fungal symbionts with expanded binding domains associated with host interactions. The evolution of these gene families should probably get some serious theoretical work that can be backed-up by population genomics since the mechanisms that generate polymorphism in expansions within populations and how these undergo selection to facilitate diversification remain something of a mystery in most of these systems.